The U.S. Food and Drug Administration is investigating the prescription drug Mirapex (generic name: pramipexole), which is used to treat Parkinson’s disease and restless legs syndrome, after recent studies suggested patients are at greater risk of heart failure. The FDA says the studies weren’t complete enough to determine whether Mirapex was the cause of heart failure, so the agency is working with the manufacturer, Boehringer Ingelheim Pharmaceuticals Inc., to determine the risk factor.
The FDA said it will issue updates on the Mirapex investigation as warranted.
Those taking Mirapex are advised to continue taking the medication, unless told otherwise by a health-care professional, and call for immediate assistance if experiencing heart-failure symptoms including:
- Shortness of breath
- Swelling of the feet, ankles, legs or abdomen
- Fatigue and weakness
- Rapid or irregular heartbeat
- Chest pain
- Persistent cough or wheezing with white or pink blood-tinged phlegm.